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|---|---|---|---|---|---|---|---|---|
| 1 | FC Cincinnati ![]() | 34 | 20 | 9 | 5 | 57:39 | 69 | W W W L |
| 2 | Orlando City SC ![]() | 34 | 18 | 9 | 7 | 55:39 | 63 | W W L |
| 3 | Columbus Crew ![]() | 34 | 16 | 9 | 9 | 67:46 | 57 | W W W |
| 4 | Philadelphia Union ![]() | 34 | 15 | 10 | 9 | 57:41 | 55 | W L |
| 5 | New England Revolution ![]() | 34 | 15 | 10 | 9 | 58:46 | 55 | L |
| 6 | Atlanta United FC ![]() | 34 | 13 | 12 | 9 | 66:53 | 51 | |
| 7 | Nashville SC ![]() | 34 | 13 | 10 | 11 | 39:32 | 49 | L L |
| 8 | New York Red Bulls ![]() | 34 | 11 | 10 | 13 | 36:39 | 43 | W L L |
| 9 | Charlotte FC ![]() | 34 | 10 | 13 | 11 | 45:52 | 43 | L |
| 10 | CF Montreal ![]() | 34 | 12 | 5 | 17 | 36:52 | 41 | |
| 11 | New York City FC ![]() | 34 | 9 | 14 | 11 | 35:39 | 41 | |
| 12 | DC United ![]() | 34 | 10 | 10 | 14 | 45:49 | 40 | |
| 13 | Chicago Fire ![]() | 34 | 10 | 10 | 14 | 39:51 | 40 | |
| 14 | Inter Miami CF ![]() | 34 | 9 | 7 | 18 | 41:54 | 34 | |
| 15 | Toronto FC ![]() | 34 | 4 | 10 | 20 | 26:59 | 22 |
| # | Team | P | W | D | L | Goals | PTS | Team Form |
|---|---|---|---|---|---|---|---|---|
| 1 | Saint Louis City FC ![]() | 34 | 17 | 5 | 12 | 62:45 | 56 | L |
| 2 | Seattle Sounders ![]() | 34 | 14 | 11 | 9 | 41:32 | 53 | W L L |
| 3 | Los Angeles FC ![]() | 34 | 14 | 10 | 10 | 54:39 | 52 | W W W L |
| 4 | Houston Dynamo ![]() | 34 | 14 | 9 | 11 | 51:38 | 51 | W L W L |
| 5 | Real Salt Lake ![]() | 34 | 14 | 8 | 12 | 48:50 | 50 | L W |
| 6 | Vancouver Whitecaps FC ![]() | 34 | 12 | 12 | 10 | 55:48 | 48 | L |
| 7 | FC Dallas ![]() | 34 | 11 | 13 | 10 | 41:37 | 46 | L W |
| 8 | Sporting Kansas City ![]() | 34 | 12 | 8 | 14 | 48:51 | 44 | W L |
| 9 | San Jose Earthquakes ![]() | 34 | 10 | 14 | 10 | 39:43 | 44 | |
| 10 | Portland Timbers ![]() | 34 | 11 | 10 | 13 | 46:58 | 43 | |
| 11 | Minnesota United FC ![]() | 34 | 10 | 11 | 13 | 46:51 | 41 | |
| 12 | Austin FC ![]() | 34 | 10 | 9 | 15 | 49:55 | 39 | |
| 13 | Los Angeles Galaxy ![]() | 34 | 8 | 12 | 14 | 51:67 | 36 | |
| 14 | Colorado Rapids ![]() | 34 | 5 | 12 | 17 | 26:54 | 27 |